Diseases of the Liver That Most people Never Hear of


Roughly 40 Million Americans are at an Increased Risk for Liver Diseases.

People Who are Obese, Those With Hepatitis C, People Taking Medications that Damage the Liver, and Those Exposed to High Levels of Environmental Toxins May be More Likely to Get Liver Diseases.

Liver Diseases Statistics

  • 1 in 10 Americans are affected by liver disease
  • Over 26,000 people in the U.S. die each year from chronic liver disease and cirrhosis
  • Cirrhosis is the 7th leading disease-related cause of death
  • 75 – 80% of cases of cirrhosis could be prevented by eliminating alcohol abuse
  • Approximately 4 Million people in the U.S. are chronically infected with Hepatitis C
  • Between 8,000 and 10,000 people die of Hepatitis C in the U.S. annually, and 1000 people have liver transplants
  • More than 200,000 people are newly infected with Hepatitis B each year in the U.S.
  • About 20% of Americans have fatty liver disease
  • Estimates of non-alcoholic fatty liver disease (NAFLD) among obese and Type 2 diabetic patients, suggest that 90% have fatty liver, 20% have non-alcoholic steatohepatitis, and 10% have cirrhosis
  • Obesity-related NAFLD is the most common liver disease world-wide



What are some common symptoms of liver disease?


To diagnose liver disease, the doctor observes the patient’s symptoms and performs a physical examination. In addition, the doctor may request a liver biopsy, liver function tests, an ultrasound, a computed tomography (CT) and / or magnetic resonance imaging (MRI).

Here are some of the most common symptoms of liver disease and a brief description of them:

  1. jaundice. Yellow eyes and skin;
  2. cholestasis;
  3. enlargement of the liver;
  4. portal hypertension;
  5. esophageal varices;
  6. ascites Accumulation of fluids in the abdominal cavity;
  7. hepatic encephalopathy


Cholestasis is any disease in which the bile flow decreases or stops. “Cole” means “bile” and “stasis” means “detention.” There may be an obstruction of the bile flow inside the liver, outside the liver or in both places.

Enlargement of the liver

Enlarged liver is a common indicator of liver disease, although there are no symptoms that are commonly associated with a slight increase in liver size (hepatomegaly).

Portal hypertension

Portal hypertension is understood to be arterial hypertension in the portal vein, which provides the liver with blood from the intestine and spleen. This can be caused by an increase in blood pressure in the blood vessels or resistance to blood flow through the liver.

Esophageal varices

Esophageal varices are dilated blood vessels within the walls of the lower part of the esophagus that are prone to bleed. They can occur in people with severe liver disease. A diseased liver can cause portal hypertension, which is high blood pressure in the portal vein.


Ascites is the accumulation of fluid in the abdominal cavity, caused by fluid loss from the surface of the liver and intestine. This diseases generally accompanies other characteristics of liver diseases such as portal hypertension.

Hepatic encephalopathy

Hepatic encephalopathy is the deterioration of brain functions and damage to the nervous system due to the accumulation of toxic substances in the blood, which are commonly filtered by the liver.

Liver failure

Hepatic insufficiency is an acute deterioration of liver function. Liver failure occurs when a large portion of the liver is damaged due to any type of liver disorder.


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